As of early summer 2025, the federal multidistrict litigation (MDL) for Depo-Provera lawsuits is gaining momentum. According to reports, more than 400 cases have been centralized in the Northern District of Florida under Judge M. Casey Rodgers. Plaintiffs allege the birth control shot caused them to develop serious brain tumors known as intracranial meningiomas, particularly with long-term use. Research suggests that spinal tumors may also be linked to Depo-Provera.
Riddle & Riddle continues to actively investigate these claims against Depo-Provera and we are ready to help however we can. For a free, no-obligation case review, please call 1-800-525-7111 or contact us via website chat.
Background on Depo-Provera Lawsuits
The lawsuits claim that Depo-Provera’s active ingredient, depot medroxyprogesterone acetate (DMPA), increases the risk of meningiomas — noncancerous but potentially dangerous brain tumors. Studies indicate the risk may be up to five times higher for women who used the shot for several years. Plaintiffs allege that the manufacturers, including Pfizer, failed to adequately warn patients and doctors about this risk.
IMPORTANT: Defendants in these lawsuits strongly deny any liability and/or wrongdoing, and there is no guarantee that Depo-Provera lawsuits will result in any settlement(s) and/or judgment(s) favorable to plaintiffs.
Status of the MDL
MDL No. 3140 was established in February 2025 to coordinate pretrial proceedings for the growing number of Depo-Provera cases. Since then, the litigation has rapidly expanded, with over 300 new cases added between March and May. As of the latest case management conference, there are more than 400 active lawsuits in the MDL.
Key Facts and Developments
- Defendants have produced nearly 1 million documents totaling over 8 million pages.
- Discovery is underway and focused on issues like causation, product labeling, and FDA preemption.
- The court is evaluating whether generic drugmakers like Greenstone, Viatris, and Prasco should remain in the litigation.
- Some generics may be dismissed from the MDL, though brand-name manufacturers may remain fully involved.
Bellwether Trials
Judge Rodgers has indicated that five bellwether cases will be selected for early trials, expected in late 2026 or early 2027. These trials are meant to test the strength of the claims and potentially guide future settlements, though their outcomes won’t directly impact other cases.
State Lawsuits
While the MDL is proceeding in federal court, other lawsuits have been filed at the state level, including in Indiana and Massachusetts. In Pennsylvania, a mass tort program for Depo-Provera has stalled, with only one case remaining after coordination was withdrawn.
What This Means for Potential Victims
Anyone who used Depo-Provera and was later diagnosed with a brain tumor or spinal trumor should consider speaking with an attorney at Riddle & Riddle Injury Lawyers. These cases often rely on clear medical records, proof of drug use, and a diagnosis from a qualified physician.
Even if you used a generic version of the drug, your case may still be valid. The MDL is moving quickly, and legal options may be time-sensitive. Don’t wait — call 1-800-525-7111 today for a free case evaluation.
Call Riddle & Riddle for Help
At Riddle & Riddle Injury Lawyers, we are actively representing individuals who may have been harmed by Depo-Provera. If you or someone you love received the shot and was later diagnosed with a brain or spinal tumor, we want to hear your story.
Call us today at 1-800-525-7111 for a free case review. There is no cost to speak with our team — and no obligation. Let us help you understand your legal rights and options.
When Justice Counts™, count on the team of Depo-Provera lawyers at Riddle & Riddle.
For more information, please contact Riddle & Riddle Injury Lawyers to schedule a free consultation with a personal injury lawyer in North Carolina today. We have twelve convenient locations in North Carolina, including Greenville, Raleigh, Goldsboro, Jacksonville, Kinston, Charlotte, Greensboro, Durham, Fayetteville, Wilmington, Winston-Salem & Garner.
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