Depo-Provera Brain and Spinal Tumor Lawsuit Lawyer

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Lawsuits Allege That Depo-Provera Causes Meningiomas

Recent lawsuits have been filed against Pfizer, the manufacturer of Depo-Provera, a contraceptive injection, alleging that it increases the risk of developing meningiomas, a type of brain tumor. Recent research has also suggested a potential link to other non-cancerous brain tumors and spinal tumors, as well as pseudotumor cerebri / idiopathic intracranial hypertension (IIH).

Plaintiffs in these cases argue that Pfizer failed to adequately warn users and healthcare providers about these serious risks. If you or a loved one has been diagnosed with a meningioma brain tumor after using Depo-Provera, you may be entitled to compensation through a Depo-Provera brain tumor lawsuit. While pseudotumor cerebri / IIH cases are not being accepted currently (as of late 2024), research is ongoing and we may be able to assist in the future — please contact out team at Riddle & Riddle Injury Lawyers or call (800) 525-7111 for a free case review.

IMPORTANT: As of January 2025, Depo-Provera manufacturer Pfizer has denied any liability and/or wrongdoing related to these lawsuits. No settlements have been agreed to and there are no guarantees concerning the outcome of this litigation.

October 2025 Update

The Depo-Provera litigation has gained traction through 2025, as more women allege that the long-acting contraceptive caused or contributed to the development of meningioma brain tumors. Key developments as of October 2025 include:

The federal MDL (MDL No. 3140) was created earlier in 2025, consolidating Depo-Provera lawsuits under Judge M. Casey Rodgers in the Northern District of Florida.
As of mid-2025, hundreds of cases have been filed in the MDL, with counts steadily rising; by September 2025, the total plaintiff count had grown to over 1,300.
Pfizer has responded with motions to dismiss, asserting that state law failure-to-warn claims are preempted because the FDA declined to allow a tumor-risk warning on the Depo-Provera label. A major upcoming hearing will test whether that preemption argument can survive in the pilot cases.
The court has designated a small number of “pilot” or “test” cases to move forward first, as a means to evaluate causation arguments, admissibility of expert testimony, and evidentiary thresholds.
Plaintiffs press that scientific studies (notably a 2024 BMJ study) have shown a strong association between progestin injections and meningioma risk, and argue Pfizer failed to disclose or update warnings in the U.S. despite doing so elsewhere.
No global settlement has been announced, and the outcome will likely depend heavily on how the court rules in the initial cases, especially on preemption, expert admissibility, and liability.
The financial exposure for defendants is uncertain, but contingent on verdicts or settlements in the pilot cases, plus the magnitude of injuries and numbers of participating plaintiffs.

As of October 2025, the Depo-Provera litigation remains in its formative but crucial phase. The decisions in the early pilot cases and on preemption will largely determine if the remaining claims proceed to discovery, settlement negotiations, or further dismissal.

Riddle & Riddle is committed to helping potential victims seek justice for injuries allegedly linked to Depo-Provera. Stay tuned to our website for the latest information on this fast-developing litigation.

Our firm is actively investigating these claims. For a FREE case review with an experienced Depo-Provera lawsuit attorney, please call (800) 525-7111 or complete the form below. There are no upfront costs, and you won’t pay any attorney fees unless we win your case and you receive financial compensation in a potential Depo-Provera settlement or verdict.

If you or a loved one has developed a brain tumor linked to Depo-Provera, you may have a legal claim. Riddle & Riddle’s skilled Depo-Provera brain tumor lawsuit lawyers are here to help you pursue the justice and compensation you deserve. Contact us today for a free consultation and let our dedicated team at Riddle & Riddle guide you through the legal process.

Depo-Provera Tumor Lawsuit Guide

What is Depo-Provera?

Depo-Provera is an injectable form of birth control that contains the synthetic hormone medroxyprogesterone acetate. It is designed to prevent pregnancy by inhibiting ovulation and thickening cervical mucus. Despite its effectiveness as a contraceptive, growing evidence has linked Depo-Provera to an increased risk of meningiomas—tumors that form on the membranes surrounding the brain and spinal cord.

The Link Between Depo-Provera and Tumors

Multiple studies have shown a connection between long-term use of Depo-Provera and the development of cerebral meningiomas. Recently published research in the Journal of the American Medical Association (JAMA) has indicated that women who have taken Depo-Provera exhibited significantly higher risk of developing these tumors.

Recently, it has been alleged that Depo-Provera may cause pseudotumor cerebri / idiopathic intracranial hypertension (IIH) and, potentially, other non-cancerous brain or spinal cord tumors. Currently, however, only brain and spinal tumors may qualify for a Depo-Provera claim. Pseudotumor cerebri / IIH cases may qualify in the future, however, as research is ongoing, so if you have suffered any of these conditions after taking Depo-Provera contraceptive injections, please call (800) 525-7111 for a free case review with one of our experienced attorneys.

Consolidation of Lawsuits: Multidistrict Litigation (MDL)

Due to the number of claims filed across various jurisdictions, many Depo-Provera brain tumor lawsuits have been consolidated into a multidistrict litigation (MDL). An MDL is a legal procedure that centralizes similar cases to streamline pretrial proceedings, conserve resources, and avoid inconsistent rulings.

Consolidation into an MDL does not affect the outcome of individual cases, but it does allow for more efficient handling of discovery, expert testimony, and other pretrial matters. If you are considering joining the Depo-Provera brain tumor lawsuit, understanding the MDL process is crucial, as it can influence the timeline and strategy of your case. During your free case review, an attorney with our firm will advise you regarding the MDL.

Compensation Available in Depo-Provera Lawsuits

If you are successful in your Depo-Provera lawsuit, you may be entitled to several types of compensation. These can include:

Medical Expenses: Covering the cost of diagnosis, treatment, and ongoing care for your meningioma.
Lost Wages: Compensation for time missed from work due to your illness and treatment.
Pain and Suffering: Damages for the physical pain and emotional distress caused by your condition.

A jury may also decide to award punitive damages in a potential verdict, intended to punish the defendant and discourage future similar behavior.

Factors That Influence Compensation Amounts

The amount of compensation you may receive in a Depo-Provera lawsuit can vary based on several factors, including the severity of your condition, the impact on your quality of life, and the strength of the evidence linking your meningioma to Depo-Provera use. Your attorney will work to ensure that all relevant factors are considered to maximize your potential compensation.

How to Qualify for a Depo-Provera Lawsuit

To pursue a Depo-Provera tumor lawsuit, you must meet specific criteria:

Use of Depo-Provera or qualifying generic alternative (at least twice): You or your loved one must have received brand-name Depo-Provera injections — or another qualifying generic alternative — at least twice
Diagnosis of cerebral meningioma, or potentially, another type of brain tumor, after use of Depo-Provera (or qualifying generic alternative): A confirmed diagnosis of cerebral meningioma, other brain tumor (cancerous or non-cancerous), typically determined through imaging tests such as an MRI or CT scan.
Documented Evidence: Medical and prescription records, as well as a detailed timeline of Depo-Provera use and the onset of symptoms, are crucial for building a strong case.

Pursuing a Depo-Provera Brain Tumor Lawsuit

Why File a Lawsuit?

Free case review - we don't get paid unless you do.

Filing a lawsuit against Pfizer may allow you to recover compensation for medical expenses, lost wages, pain and suffering, and other damages associated with your diagnosis. Moreover, holding pharmaceutical companies accountable for their products’ safety can prevent future harm to others.

If you’ve suffered from meningioma(s) after receiving the Depo-Provera injection(s), call (800) 525-7111 for a FREE case review with an experienced dangerous drugs attorney. We will listen to you, review your claim and associated evidence, and advise you on your best available legal options, which may include filing a Depo-Provera lawsuit and joining the potential MDL.

Those who have suffered from brain tumors potentially linked to Depo-Provera deserve justice, and we’re determined to help them get it.

-Gene Riddle, Depo-Provera attorney

What to Expect

Your lawsuit will involve gathering detailed medical records, securing expert testimony, and establishing a clear link between your use of Depo-Provera and the diagnosis of meningioma, or a different type of brain or spinal tumor. Your attorney will guide you through each step, including settlement negotiations or going to trial if necessary.

Contact Us for a Free Case Review

If you or a loved one has been diagnosed with a meningioma after using Depo-Provera, it’s essential to seek legal advice immediately. Our experienced dangerous drug attorneys routinely handle product liability cases and are dedicated to helping clients secure the compensation they deserve. We understand the profound impact a brain tumor diagnosis can have on your life, and we’re here to support you every step of the way.

Call our law firm today at (800) 525-7111 today for a free, no-obligation case review. We’ll evaluate your case, provide expert advice, and help you decide on the best course of action. Your health and well-being are our top priorities—don’t wait to get the legal help you need.

Justice Counts.

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