Justice for Victims of Injuries Potentially Linked to Sickle Cell Drugs
If you or a loved one took Oxbryta (voxelotor) to manage sickle cell disease (SCD) and experienced serious complications or death, you may be eligible for compensation in an Oxbryta lawsuit. Riddle & Riddle Injury Lawyers are actively investigating claims and filing Oxbryta lawsuits on behalf of individuals and families harmed by this drug. Call 1-800-525-7111 today for a free, no-obligation case review.
Oxbryta was designed to help those suffering from sickle cell disease by improving oxygen delivery and reducing hemolysis. But instead of relief, some patients have experienced worsened health outcomes, including increased vaso-occlusive crises, organ failure, infections, and other severe complications. In the most tragic cases, patients have died following regular use of the drug. These heartbreaking outcomes may be linked to Oxbryta.
Our firm, Riddle & Riddle Injury Lawyers, is ready to help potential victims however we can. Please call 1-800-525-7111 for a free case review. Remember, if you qualify for an Oxbryta sickle cell disease lawsuit and decide to hire us, there are no upfront costs and we don’t get paid unless you do.
What Is Oxbryta?
Oxbryta (voxelotor) is an FDA-approved medication for sickle cell disease, a condition that causes red blood cells to become misshapen and leads to pain, anemia, and organ damage. By preventing hemoglobin from sticking together, Oxbryta helps improve oxygen delivery throughout the body and reduces the complications associated with SCD.
It was developed by Global Blood Therapeutics and approved by the FDA in November 2019 for patients 12 and older. In December 2021, its use was expanded to children as young as 4. The drug works by binding to hemoglobin in red blood cells, aiming to prevent the sickling process that causes many of the painful and life-threatening symptoms of SCD.
While marketed as a groundbreaking treatment, reports have emerged suggesting that Oxbryta may cause or worsen serious health conditions. Riddle & Riddle is committed to holding pharmaceutical companies accountable when their products harm patients.
Oxbryta Recall and FDA Warning
In 2024, the manufacturer of Oxbryta (voxelotor) voluntarily withdrew the drug from the market following reports of potential contamination issues with specific lots. The FDA subsequently issued a safety alert to inform healthcare providers and patients of the Oxbryta recall, emphasizing the importance of discontinuing use of the affected product.
While the recall was initiated as a precautionary measure, the FDA advised patients to consult their healthcare providers for alternative treatment options and closely monitor for adverse effects. The agency continues to evaluate the situation to ensure patient safety.
Why Are Oxbryta Lawsuits Being Filed?
Oxbryta lawsuits claim that the drug has been linked to several serious health issues, including:
- Liver damage and dysfunction
- Cardiovascular problems
- Stroke
- Blood clots
- Arthritis
- Severe fatigue and weakness
- Unexplained hospitalizations
- Death
Plaintiffs allege that Global Blood Therapeutics failed to warn about these risks adequately. Some lawsuits further suggest that the company may have minimized adverse event reports during clinical trials to gain FDA approval more quickly.
Global Blood Therapeutics has strongly denied these claims, asserting that Oxbryta is safe and effective for treating sickle cell disease when prescribed as directed.
INJURIES AND COMPPLICATIONS Linked to Oxbryta
Oxbryta users have reported a wide range of severe complications potentially linked to this medication. According to current investigations, research, and medical documentation, the following health issues may be linked to Oxbryta:
- Increased frequency of vaso-occlusive crises (pain episodes caused by blocked blood flow)
- Acute chest syndrome (a leading cause of death among SCD patients)
- Hepatic (liver) failure
- Kidney failure
- Blood clots
- Bone necrosis or arthritis
- Stroke
- Vision loss
- Pulmonary hypertension
- Splenic sequestration (a potentially fatal condition involving the spleen)
- Sleep-disordered breathing or sleep apnea
- Serious infections, including pneumonia
- Leg ulcers
- Priapism (prolonged, painful erections)
- Death
These complications can be debilitating or fatal. If you or your loved one took Oxbryta and suffered any of the above health issues, you may have a case. But time is of the essence — it’s essential to contact an experienced Oxbryta attorney right away.
Please call 1-800-525-7111 for a free case review with our experienced legal team.
CRITERIA FOR FILING an Oxbryta Lawsuit
Riddle & Riddle Injury Lawyers is reviewing Oxbryta cases that meet the following criteria:
- The person took Oxbryta after November 25, 2019 (if they were 12 or older at first use)
- OR the person took Oxbryta after December 17, 2021 (if they were 4 or older at first use)
- They must have been diagnosed with a variant of sickle cell disease
- They must have taken Oxbryta at least once daily
- There must be medical documentation showing the development or worsening of one or more of the following conditions after starting Oxbryta:
- Vaso-occlusive crises
- Acute chest syndrome
- Hepatic or kidney failure
- Stroke or blood clots
- Serious infections such as pneumonia
- Bone necrosis, arthritis, or leg ulcers
- Pulmonary hypertension or vision loss
- Priapism or splenic sequestration
- Sleep apnea or other sleep-disordered breathing
- Death following consistent use
If you believe your case meets these conditions, contact us immediately at 1-800-525-7111 Time may be limited to file a claim or Oxbryta lawsuit.
Why Are Oxbryta Lawsuits Being Filed?
Patients and families allege that Global Blood Therapeutics, acquired by Pfizer, failed to adequately warn doctors and patients about the risks associated with Oxbryta. In some cases, the side effects were more severe than the symptoms of sickle cell disease itself. Key allegations include:
- Failure to warn about severe complications such as liver damage, infections, or death
- Defective design or testing of the drug prior to approval
- Negligence in monitoring safety after release
- Misleading marketing about the effectiveness and safety of Oxbryta
Drug manufacturers have a legal responsibility to ensure their products are safe. When they fail, Riddle & Riddle fights to make sure Justice Counts.
How Our Oxbryta Lawsuit Lawyers Can Help
Riddle & Riddle Injury Lawyers bring decades of experience and a track record of success to complex product liability and dangerous drug cases. When you work with our team, we:
- Offer a free case review and consultation
- Investigate your case thoroughly, gathering medical records and expert opinions
- File your Oxbryta lawsuit if you qualify
- Work on a contingency fee basis — you won’t pay any attorney fees unless we win your case
Our experienced team has recovered over $850 million in compensation for clients since 2000 alone (see disclaimer below). With more than 190 years of combined legal experience among our many attorneys, we have the resources and skill to take on large pharmaceutical companies and win.
Call Now for a Free Consultation
If you or a loved one suffered serious complications after taking Oxbryta for sickle cell disease, don’t wait. Our legal team is standing by to evaluate your case and help you understand your options. Call 1-800-525-7111 for a free, confidential consultation today.
Why Riddle & Riddle for Your Oxbryta Lawsuit?
- Over $850 million recovered for our clients since 2000 (see disclaimer below)
- More than 190 years of combined legal experience
- Nationally recognized attorneys with memberships in the National Trial Lawyers Top 100, Super Lawyers, and Multi-Million Dollar Advocates Forum, among other prestigious organizations (see disclaimer below)
- We handle complex product liability and pharmaceutical lawsuits with a proven record of success
- Client-centered advocacy with compassion, transparency, and relentless pursuit of justice — in 2025, we were named a “Best Family-Run Law Firm” by NC Lawyers Weekly (see disclaimer below)
When Justice Counts™, we can help you fight back. Call 1-800-525-7111 now.
“This settlement changed me and my family’s lives.”
-Linda B., Riddle & Riddle client
Frequently Asked Questions About Oxbryta Lawsuits
What is the deadline to file an Oxbryta lawsuit?
Each state has a statute of limitations, or legal deadline, for filing product liability claims. In many states, it ranges from 1 to 3 years from the date of injury or discovery of harm. Contact us as soon as possible to avoid losing your right to compensation.
Do I qualify if my child took Oxbryta and experienced complications?
Yes. If your child was prescribed Oxbryta at age 4 or older after December 17, 2021, and experienced qualifying complications, your family may have a case. Call 1-800-525-7111 to learn more.
What compensation can I recover in an Oxbryta lawsuit?
Compensation may include:
- Medical expenses
- Pain and suffering
- Lost wages
- Funeral expenses (in cases of wrongful death)
- Other damages related to your or your loved one’s injuries
What will it cost me to file an Oxbryta lawsuit?
If you qualify and decide to file a lawsuit, nothing up front. Riddle & Riddle works on a contingency fee basis, which means you pay no attorney fees unless we recover compensation for you.
How long will the lawsuit take?
Every case is different, but drug injury lawsuits often take a long time — sometimes 1, 2 or even 3+ years to resolve, especially when cases are consolidated into an MDL. If you qualify and decide to hire us, our team will keep you informed every step of the way.
Don’t wait. If Oxbryta potentially caused harm to you or your loved one, justice may be just a phone call away. Call 1-800-525-7111 now for your free case evaluation.
Compensation Available for Oxbryta Lawsuits
If your lawsuit is successful, you may be entitled to compensation for:
- Medical expenses, including hospital stays and treatments
- Lost wages due to time away from work
- Pain and suffering
- Emotional distress
- Other damages related to your injuries
Every case is unique, and the amount of compensation will depend on the specifics of your claim. If you qualify for a lawsuit, Riddle & Riddle can help you pursue the maximum compensation available under the law.
When you work with Riddle & Riddle, you’ll receive personalized attention from an experienced legal team that is dedicated to achieving the best possible outcome for your case. Call 1-800-525-7111 today for your free, no-obligation case review. Let us fight for you while you focus on your recovery.
There are no upfront costs and you won't pay any attorney fees unless we win your case — and you receive compensation.
If you or a loved one have suffered severe health issues linked to Oxbryta, don’t wait to seek help. Call 1-800-525-7111 now to speak with a personal injury attorney and learn more about your legal options.