What Health Problems Does PFAS Cause?

February 18, 2025 | By Riddle & Riddle Injury Lawyers
What Health Problems Does PFAS Cause?

Understanding the Health Risks of PFAS Contamination

Per- and polyfluoroalkyl substances (PFAS) are a group of human-made chemicals that have been widely used in industrial applications and consumer products for decades. These chemicals have been linked to various health risks, including cancer, liver damage, kidney disease, immune system suppression, fertility issues, thyroid disorders, and cardiovascular diseases. Research into the long-term health effects of PFAS exposure is ongoing, but mounting evidence has led to increased public concern and escalating litigation against manufacturers. If you or a loved one has been exposed to PFAS-contaminated water or products, you may be eligible for a PFAS lawsuit. Contact Riddle & Riddle Injury Lawyers for a free case review at 1-800-525-7111.

Our firm is actively investigating claims that PFAS contamination causes serious health problems and we are ready to help however we can. There are no upfront costs and we don't get paid unless you do. Call 1-800-525-7111 and let's review your claim for free.

Understanding the Health Risks of PFAS Contamination

What Are PFAS?

PFAS are synthetic chemicals that have been used since the 1940s in products that resist heat, water, and grease. These chemicals are often referred to as "forever chemicals" because they do not break down easily and accumulate in the environment and human body over time. PFAS exposure primarily occurs through contaminated water, food, and consumer products.

Common Sources of PFAS Contamination

PFAS contamination is widespread, affecting water supplies, soil, and even food. Some of the most common sources include:

  • Drinking Water: Contaminated by industrial discharge, military bases, and firefighting foam (AFFF).
  • Food Packaging: Used in grease-resistant wrappers, fast food containers, and microwave popcorn bags.
  • Household Products: Found in stain-resistant carpets, nonstick cookware (like Teflon), and water-repellent clothing.
  • Industrial Sites: Factories manufacturing electronics, textiles, and other goods release PFAS into local water supplies.
  • Firefighting Foam (AFFF): Heavily used in military and civilian airports, leading to extensive groundwater contamination.

Health Problems Linked to PFAS Exposure

Research is ongoing, but current evidence strongly suggests that long-term exposure to PFAS can cause serious health problems, including the following.

IMPORTANT: If you've experienced any symptoms of the following health problems, seek medical care immediately.

1. Cancer

PFAS exposure has been associated with an increased risk of several types of cancer, including kidney cancer, testicular cancer, and liver cancer. According to the American Cancer Society, research also suggests a potential link between PFAS chemicals and other types of cancer, including prostate cancer, bladder cancer, breast cancer, and ovarian cancer. However, research exploring potential connections between PFAS and cancer is ongoing.

These chemicals can accumulate in the body over time, leading to cell damage and increasing the likelihood of malignant growths. The long-term exposure to even low levels of PFAS may be enough to trigger cancer development, making this a significant public health concern.

How PFAS Contributes to Cancer Development

  • PFAS disrupts cellular processes, leading to abnormal cell growth.
  • It induces oxidative stress, which can cause DNA mutations.
  • The chemicals interfere with hormone regulation, potentially triggering hormone-related cancers such as breast and prostate cancer.

2. Liver and Kidney Damage

The liver plays a crucial role in filtering toxins from the bloodstream, and PFAS exposure has been linked by research to liver dysfunction. People with prolonged PFAS exposure have shown increased levels of liver enzymes, which indicate liver stress or damage. Additionally, research demonstrates that PFAS can affect kidney function, potentially leading to chronic kidney disease or decreased filtration efficiency. Given the essential role of the kidneys in detoxifying the body, any impairment in their function can have serious long-term consequences.

Signs of Liver and Kidney Damage Due to PFAS

  • Fatigue and general weakness
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine and light-colored stool
  • Swelling in the legs and abdomen
  • Frequent urinary tract infections or difficulty urinating

3. Immune System Suppression

The immune system is vital for protecting against infections and diseases, and PFAS exposure has been shown to weaken immune function. Studies have indicated that PFAS can reduce vaccine effectiveness, increase susceptibility to infections, and contribute to autoimmune disorders. This is particularly concerning for children and the elderly, who rely on robust immune responses to maintain their health. Lupus, rheumatoid arthritis, and inflammatory bowel disease (IBD) have been observed in individuals with prolonged PFAS exposure. Additionally, PFAS may contribute to thyroid-related autoimmune disorders like Hashimoto’s thyroiditis and Graves’ disease, further exacerbating hormonal imbalances and metabolic disruptions.

How PFAS Affects the Immune System

  • Lowers white blood cell count, making infections more likely
  • Disrupts the production of antibodies, reducing vaccine efficacy
  • Increases inflammation, which can lead to chronic autoimmune disorders

4. Reproductive and Developmental Issues

PFAS exposure has been linked to reproductive health problems in both men and women. Women exposed to high levels of PFAS may experience decreased fertility, irregular menstrual cycles, and pregnancy complications. Additionally, infants exposed to PFAS in the womb are more likely to be born with lower birth weights, developmental delays, and potential cognitive impairments. These effects highlight the serious generational impact of PFAS contamination.

PFAS and Male Fertility

  • Reduced sperm count and quality
  • Increased risk of erectile dysfunction
  • Hormonal imbalances affecting testosterone production

5. Thyroid Disease

The thyroid gland regulates metabolism and overall hormonal balance. PFAS can interfere with thyroid hormone production, leading to conditions such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). Symptoms of thyroid dysfunction include fatigue, weight gain or loss, mood swings, and difficulty regulating body temperature. Over time, untreated thyroid conditions can lead to severe metabolic and cardiovascular problems.

PFAS Found in water

Symptoms of PFAS-Induced Thyroid Dysfunction

  • Unexplained weight gain or loss
  • Depression or anxiety
  • Hair thinning or excessive hair loss
  • Sensitivity to heat or cold
  • Difficulty concentrating (brain fog)

6. High Cholesterol and Cardiovascular Disease

Research has shown a strong link between PFAS exposure and elevated cholesterol levels. Increased cholesterol can contribute to a higher risk of heart disease, stroke, and other cardiovascular complications. Individuals with prolonged exposure to PFAS may also experience increased blood pressure, which further exacerbates the risk of heart-related health issues.

How PFAS Affects Heart Health

  • Hardens arteries, increasing risk of hypertension and stroke
  • Disrupts lipid metabolism, raising LDL (bad cholesterol)
  • Increases inflammation, contributing to heart disease progression

Have you suffered due to PFAS contamination?

Escalating PFAS Litigation

As awareness of PFAS contamination grows, lawsuits against manufacturers and companies responsible for PFAS pollution have surged. Several major legal actions have already resulted in significant settlements, with plaintiffs including municipalities, military personnel, firefighters, and individuals suffering from PFAS-related health conditions.

The Future of PFAS Lawsuits

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Legal experts anticipate a growing number of PFAS lawsuits as more scientific studies confirm the dangers of exposure. The U.S. government has also taken steps to regulate PFAS, which may strengthen the legal claims of affected individuals.

If you or a loved one has suffered from health issues potentially caused by PFAS, you may be entitled to compensation. Contact Riddle & Riddle Injury Lawyers for a free case evaluation at 1-800-525-7111. At Riddle & Riddle, we are proud to be headquartered in North Carolina, a state that has experienced extensive PFAS contamination in public water sources. We understand the extreme danger that PFAS chemicals can pose to local communities across the country, and we are ready to help however we can.

Please call 1-800-525-7111 for a free case review with an experienced attorney handling PFAS injury claims.

What to Do If You Were Exposed to PFAS

If you believe you were exposed to PFAS through contaminated water, products, or workplace exposure, take the following steps:

  1. Consult a Medical Professional: Get tested for PFAS levels in your blood and monitor any health symptoms. If you experience any symptoms potentially related to PFAS contamination, seek medical attention immediately.
  2. Reduce Further Exposure: Switch to a water filtration system certified to remove PFAS and avoid products containing these chemicals.
  3. Document Your Exposure: Keep records of where and how you were exposed, including medical diagnoses and any regulatory notices about contamination in your area.
  4. Seek Legal Help: Speak with an experienced PFAS attorney at Riddle & Riddle Injury Lawyers to determine if you may qualify for a PFAS claim or lawsuit. Call 1-800-525-7111 today for a free case review.

Contact Riddle & Riddle Injury Lawyers for a Free Case Review

The legal landscape surrounding PFAS contamination is evolving rapidly. If you have suffered health issues potentially linked to PFAS exposure, don’t wait to take action. Contact Riddle & Riddle Injury Lawyers today for a free, no-obligation case review at 1-800-525-7111. Our legal team is dedicated to fighting for victims' rights and holding potentially negligent companies accountable.

Since 2000 alone, Riddle & Riddle's experienced PFAS lawyers have recovered over $800 million for clients injured due to others' negligence (see disclaimer below). Led by managing partner Gene Riddle and his daughter, partner Alex Riddle, our firm's attorneys have been recognized for their experience and results by such prestigious organizations and awards as Multi-Million Dollar Advocates Forum, The National Trial Lawyers Top 100, Super Lawyers, The National Association of Distinguished Counsel, and others (see disclaimer below).

"This settlement changed me and my family's lives."

Have You Suffered Due to PFAS Contamination?

-Linda B., Riddle & Riddle client

When Justice Counts™, our experienced PFAS attorneys are ready to help however we can. Don't wait — call 1-800-525-7111 today to protect your legal rights and see if you may qualify for compensation in a PFAS lawsuit.